Phenylbutazone and sodium salicylate are both nonsteroidal anti-
inflammatory drugs (NSAIDs) with analgesic effects to relieve pain and
antipyretic effects to relieve fever. The rapid action of sodium salicylate
combines with the longer-term activity of phenylbutazone to present an
excellent option for the treatment and management of musculoskeletal
pain in horses. Phenylbutazone shows well documented and proven
effectiveness in the treatment of musculoskeletal conditions in horses.
Sodium salicylate is an antipyretic analgesic agent.
For the relief of musculoskeletal pain in horses. Suitable conditions for
treatment include arthritis, arthrosis, bursitis, osteoarthritis, tendonitis,
tenosynovitis and inflammation of the skin and soft tissues. When used
as part of the management of febrile conditions, the underlying cause
of the fever must also be treated.
DOSAGE AND ADMINISTRATION
For adult horses and foals initially administer 10 – 20 mL per 450 kg
(1 – 2 mL/45 kg) per day by slow intravenous injection.
According to the response to initial treatment, dosage can be reduced
to 5 – 10 mL per 450 kg (0.5 – 1 mL/45 kg) per day and continued for
5 – 6 days as required.
Contraindications: in horses with severe hepatic, renal or cardiac
disease; gastrointestinal disease, particularly gastrointestinal ulceration
and haemorrhage; history of blood disorders.
Adverse reactions: to phenylbutazone and sodium salicylate are rare
however gastric irritation, jaundice, limb oedema and blood dyscrasias
have been reported.
If used in performance animals, the regulations of the relevant
authorities regarding medication should be observed.
Meat Withholding Period (Horses): NOT TO BE USED in horses intended
for human consumption.